Recently, good news came that Jiudian Hongyang's API Polaprezinc (Y20230000678) was registered as "A" in the Center for Drug Evaluation (CDE) of the NMPA and has been successfully approved for marketing.

Polaprezinc is a new generation of anti-gastric ulcer drugs and the first zinc-containing compound used in clinical practice. It has a high affinity with the gastric mucosa and can adhere for a long time. It can directly protect cells through antioxidant and membrane stabilization effects, and promote wound healing through tissue repair. Polaprezinc is a chelate of L-carnosine and zinc. In addition to the advantages of zinc, the L-carnosine it contains can also promote granulation tissue regeneration and ulcer healing. It is used for peptic ulcers and Hp eradication or has more advantages than other zinc preparations. Polaprezinc has been widely used in Japan since 1994. Many years of clinical application on the market have proved that it is an effective and safe anti-gastric ulcer drug.

Among patients with gastric ulcers, the infection rate of Helicobacter pylori (Hp) is as high as more than 90%. In recent years, although the decline in Helicobacter pylori infection rates and the popularization of anti-secretory drugs have reduced the total number of gastric ulcer patients, the difficulty of diagnosis and treatment of non-Hp-related ulcers (such as ulcers caused by long-term use of non-steroidal anti-inflammatory drugs and glucocorticoids) has increased significantly. As a new generation of anti-gastric ulcer drugs, the sales of Polaprezinc preparations  achieved sales exceeding 150 million RMB  in China in 2023, indicating a broad market potential.

The approval of Polaprezinc raw materials for listing is an important achievement of Jiudian Hongyang's adherence to the innovation-driven development strategy, and it is also a powerful manifestation of the company's deep cultivation in the field of digestive system disease treatment. In the future, Jiudian Hongyang will continue to increase R&D investment and continuously launch more high-quality and efficient products.